InhaltsangabeVolume 1: PRINCIPLES OF TUMOR TARGETING Limits of Conventional Cancer Chemotherapy Pathophysiological and Vascular Characteristics of Tumors in Relation to Drug Delivery Enhanced Permeability and Retention Effect in Relation to Tumor Targeting Pharmacokinetics of Immunoglobulin G and Serum Albumin: Impact of the Neonatal Fc Receptor on Drug Design Development of Cancer-Targeting Ligands and Ligand-Drug Conjugates AntibodyDirected Enzyme Prodrug Therapy (ADEPT) Basic Principles and its Practice So Far TUMOR IMAGING Imaging Techniques in Drug Development and Clinical Practice Magnetic Nanoparticles in Magnetic Resonance Imaging and Drug Delivery Preclinical and Clinical Tumor Imaging with SPECT/CT and PET/CT Volume 2: MACROMOLECULAR DRUG DELIVERY SYSTEMS AntibodyBased Systems Empowered Antibodies for Cancer Therapy Mapping Accessible Vascular Targeting to Penetrate Organs and Solid Tumors Considerations of Linker Technologies AntibodyMaytansinoid Conjugates: From the Bench to the Clinic Calicheamicin Antibody-Drug Conjugates and Beyond Antibodies for the Delivery of Radionuclides Bispecific Antibodies and Immune Therapy Targeting POLYMERBASED SYSTEMS Design of Polymer-Drug Conjugates Dendritic Polymers in Oncology: Facts, Features, and Applications SiteSpecific Prodrug Activation and the Concept of SelfImmolation LigandAssisted Vascular Targeting of Polymer Therapeutics Drug Conjugates with Poly(Ethylene)Glycole ThermoResponsive Polymers Polysaccharide-Based Drug Conjugates for Tumor Targeting Serum Proteins as Drug Carriers of Anticancer Agents Future Trends, Challenges, and Opportunities with Polymer-Based Combination Therapy in Cancer Clinical Experience with Drug-Polymer Conjugates NANO AND MICROPARTICULATE DRUG DELIVERY SYSTEMS LIPIDBASED SYSTEMS Overview on Nanocarriers as Delivery Systems Development of PEGylated Liposomes Immunoliposomes Responsive Liposomes (for Solid Tumor Therapy) Nanoscale Delivery Systems for Combination Chemotherapy NANO AND MICROPARTICULATE DRUG DELIVERY SYSTEMS POLYMERBASED SYSTEMS Micellar Strcutures as Drug Delivery Systems TailorMade Hydrogels for Tumor Delivery pHTriggered Micelles for Tumor Delivery AlbuminDrug Nanoparticles Carbon Nanotubes Volume 3: LIGANDBASED DRUG DELIVERY SYSTEMS CellPenetrating Peptides in Cancer Targeting Targeting to Peptide Receptors Aptamer Conjugates: Emerging Delivery Platforms for Targeted Cancer Therapy Design and Synthesis of Drug Conjugates of Vitamins and Growth Factors Drug Conjugates with Polyunsaturated Fatty Acids SPECIAL TOPICS RNA Drug Delivery Approaches Local Gene Delivery for Therapy of Solid Tumors Viral Vectors for RNA Interference Applications in Cancer Research and Therapy Design of Targeted Protein Toxins Drug Targeting to the Central Nervous System Liver Tumor Targeting Photodynamic Therapy: Photosensitizers Targeting and Delivery TumorTargeting Strategies with Anticancer Platinum Complexes

InhaltsangabeVolume 1: PRINCIPLES OF TUMOR TARGETING Limits of Conventional Cancer Chemotherapy Pathophysiological and Vascular Characteristics of Tumors in Relation to Drug Delivery Enhanced Permeability and Retention Effect in Relation to Tumor Targeting Pharmacokinetics of Immunoglobulin G and Serum Albumin: Impact of the Neonatal Fc Receptor on Drug Design Development of Cancer-Targeting Ligands and Ligand-Drug Conjugates AntibodyDirected Enzyme Prodrug Therapy (ADEPT) Basic Principles and its Practice So Far TUMOR IMAGING Imaging Techniques in Drug Development and Clinical Practice Magnetic Nanoparticles in Magnetic Resonance Imaging and Drug Delivery Preclinical and Clinical Tumor Imaging with SPECT/CT and PET/CT Volume 2: MACROMOLECULAR DRUG DELIVERY SYSTEMS AntibodyBased Systems Empowered Antibodies for Cancer Therapy Mapping Accessible Vascular Targeting to Penetrate Organs and Solid Tumors Considerations of Linker Technologies AntibodyMaytansinoid Conjugates: From the Bench to the Clinic Calicheamicin Antibody-Drug Conjugates and Beyond Antibodies for the Delivery of Radionuclides Bispecific Antibodies and Immune Therapy Targeting POLYMERBASED SYSTEMS Design of Polymer-Drug Conjugates Dendritic Polymers in Oncology: Facts, Features, and Applications SiteSpecific Prodrug Activation and the Concept of SelfImmolation LigandAssisted Vascular Targeting of Polymer Therapeutics Drug Conjugates with Poly(Ethylene)Glycole ThermoResponsive Polymers Polysaccharide-Based Drug Conjugates for Tumor Targeting Serum Proteins as Drug Carriers of Anticancer Agents Future Trends, Challenges, and Opportunities with Polymer-Based Combination Therapy in Cancer Clinical Experience with Drug-Polymer Conjugates NANO AND MICROPARTICULATE DRUG DELIVERY SYSTEMS LIPIDBASED SYSTEMS Overview on Nanocarriers as Delivery Systems Development of PEGylated Liposomes Immunoliposomes Responsive Liposomes (for Solid Tumor Therapy) Nanoscale Delivery Systems for Combination Chemotherapy NANO AND MICROPARTICULATE DRUG DELIVERY SYSTEMS POLYMERBASED SYSTEMS Micellar Strcutures as Drug Delivery Systems TailorMade Hydrogels for Tumor Delivery pHTriggered Micelles for Tumor Delivery AlbuminDrug Nanoparticles Carbon Nanotubes Volume 3: LIGANDBASED DRUG DELIVERY SYSTEMS CellPenetrating Peptides in Cancer Targeting Targeting to Peptide Receptors Aptamer Conjugates: Emerging Delivery Platforms for Targeted Cancer Therapy Design and Synthesis of Drug Conjugates of Vitamins and Growth Factors Drug Conjugates with Polyunsaturated Fatty Acids SPECIAL TOPICS RNA Drug Delivery Approaches Local Gene Delivery for Therapy of Solid Tumors Viral Vectors for RNA Interference Applications in Cancer Research and Therapy Design of Targeted Protein Toxins Drug Targeting to the Central Nervous System Liver Tumor Targeting Photodynamic Therapy: Photosensitizers Targeting and Delivery TumorTargeting Strategies with Anticancer Platinum Complexes

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