InhaltsangabePart I: The G Protein-Coupled Receptor in the Genome 1. In Silico Identification of Novel G Protein-Coupled Receptors            Matthew N. Davies, David E. Gloriam, and Darren R. Flower 2. Alternative Pre-mRNA Splicing of G Protein-Coupled Receptors            Ying-Xian Pan, Steven Grinnell, and Gavril W. Pasternak 3. Detecting Polymorphisms in G Protein-Coupled Receptor Genes            Dmitri Proudnikov, Vadim Yuferov, and Mary Jeanne Kreek 4. Regulation of the Transcription of G Protein-Coupled Receptor Genes            Cheol Kyu Hwang, Ping-Yee Law, Li-Na Wei, and Horace H. Loh 5. Deciphering the Evolution of G Protein-Coupled Receptors in Vertebrates            Craig W. Stevens Part II: The Trafficking of G Protein-Coupled Receptors 6. A New Approach to Visualize Endogenously Expressed G Protein-Coupled Receptors in Tissues and Living Cells            Brigitte L Kieffer and Grégory Scherrer 7. Post-Translational Regulation of G Protein-Coupled Receptors            Yu Qiu and Ping-Yee Law 8. Discovering G Protein-Coupled Receptor Motifs Mediating Export from the Endoplasmic Reticulum            Chunmin Dong and Guangyu Wu 9. Identifying G Protein-Coupled Receptor Escorts, Chaperones, and Intracellular Tethers Regulating Receptor Density at the Cell Surface            Stefano Marullo, Liliana Pardo Lopez, and Lamia Achour 10. A Novel Method for Determining the Kinetics of G Protein-Coupled Receptor Plasma Membrane Expression            Gregory W. Sawyer Part III: The G Protein-Coupled Receptor on the Membrane 11. Characterizing the Pharmacology of G Protein-Coupled Receptors in Transfected Cell Lines            Kathryn A. Seely and Paul L. Prather 12. Novel Assay Technologies for the Discovery of G Protein-Coupled Receptor Drugs            Elisa Alvarez-Curto, Richard J. Ward, and Graeme Milligan 13. Discovering Cell-Type-Specific Patterns of G Protein-Coupled Receptor Phosphorylation            Kok Choi Kong, Andrew B. Tobin, and Adrian J. Butcher 14. Quantifying Allosteric Modulation of G Protein-Coupled Receptors            Frederick J. Ehlert and Hinako Suga 15. Experimental Designs for the Study of Receptor-Receptor Interactions            Dennis Paul Part IV: The Regulation of G Protein-Coupled Receptors 16. Elucidating Agonist-Selective Mechanisms of G Protein-Coupled Receptor Desensitization            Chris P. Bailey and Eamonn Kelly 17. Detecting the Role of Arrestins in G-Protein Coupled Receptor Regulation            Laura M. Bohn and Patricia H. McDonald 18. Characterizing Molecular Mobility and Membrane Interactions of G Protein-Coupled Receptors            Vladana Vukojevic, Yu Ming, and Lars Terenius 19. Using RNA Interference to Downregulate G Protein-Coupled Receptors            Philippe Sarret, Louis Doré-Savard, Pascal Tétreault, Valérie Bégin-Lavallée, Marc-André Dansereau, and Nicolas Beaudet 20. Upregulating G Protein-Coupled Receptors with Receptor Antagonists            Ellen M. Unterwald